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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
14.24
Human Site:
Y1042
Identified Species:
24.1
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
Y1042
K
L
D
S
S
D
I
Y
N
E
L
K
E
T
Y
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
Y1042
K
L
D
S
S
D
I
Y
N
E
L
K
E
T
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
K1042
T
E
A
L
R
D
L
K
I
Q
W
M
T
K
L
Rat
Rattus norvegicus
Q64560
1249
138274
Y1042
K
L
D
S
T
D
I
Y
N
E
L
K
E
T
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
K1147
A
E
A
L
R
D
L
K
I
Q
W
M
T
K
L
Chicken
Gallus gallus
XP_425591
1248
138209
Y1041
K
L
D
T
P
D
V
Y
N
E
L
K
E
A
F
Frog
Xenopus laevis
NP_001085380
1261
139671
Q1043
A
L
R
D
L
K
I
Q
W
M
S
K
L
E
S
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
W409
L
P
P
N
Q
Y
T
W
S
S
R
G
P
C
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
V1157
T
P
Q
A
A
T
S
V
T
N
P
A
A
G
D
Honey Bee
Apis mellifera
XP_395521
1450
161968
W1050
L
R
D
F
K
C
S
W
L
T
K
L
E
P
G
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
A1098
Q
K
L
T
D
E
K
A
A
K
E
F
F
E
A
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
S1029
D
M
K
I
S
W
L
S
K
L
E
G
D
E
L
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
K1083
I
R
V
V
S
S
L
K
Q
D
T
D
E
E
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
E1162
F
L
G
N
L
K
Q
E
T
E
E
E
R
S
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
6.6
93.3
N.A.
6.6
66.6
20
0
N.A.
0
13.3
0
6.6
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
20
100
N.A.
20
86.6
20
20
N.A.
13.3
20
26.6
26.6
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
15
8
8
0
0
8
8
0
0
8
8
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
36
8
8
43
0
0
0
8
0
8
8
0
8
% D
% Glu:
0
15
0
0
0
8
0
8
0
36
22
8
43
29
8
% E
% Phe:
8
0
0
8
0
0
0
0
0
0
0
8
8
0
8
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
15
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
29
0
15
0
0
0
0
0
0
% I
% Lys:
29
8
8
0
8
15
8
22
8
8
8
36
0
15
0
% K
% Leu:
15
43
8
15
15
0
29
0
8
8
29
8
8
0
22
% L
% Met:
0
8
0
0
0
0
0
0
0
8
0
15
0
0
0
% M
% Asn:
0
0
0
15
0
0
0
0
29
8
0
0
0
0
0
% N
% Pro:
0
15
8
0
8
0
0
0
0
0
8
0
8
8
0
% P
% Gln:
8
0
8
0
8
0
8
8
8
15
0
0
0
0
0
% Q
% Arg:
0
15
8
0
15
0
0
0
0
0
8
0
8
0
8
% R
% Ser:
0
0
0
22
29
8
15
8
8
8
8
0
0
8
8
% S
% Thr:
15
0
0
15
8
8
8
0
15
8
8
0
15
22
8
% T
% Val:
0
0
8
8
0
0
8
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
15
8
0
15
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
29
0
0
0
0
0
0
22
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _